Ex Vivo Expansion of Human CD8(+) T Cells Using Autologous CD4(+) T Cell Help

BACKGROUND: Using in vivo mouse models, the mechanisms of CD4(+) T cell help have been intensively investigated. However, a mechanistic analysis of human CD4(+) T cell help is largely lacking. Our goal was to elucidate the mechanisms of human CD4(+) T cell help of CD8(+) T cell proliferation using a...

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Detalles Bibliográficos
Autores principales: Butler, Marcus O., Imataki, Osamu, Yamashita, Yoshihiro, Tanaka, Makito, Ansén, Sascha, Berezovskaya, Alla, Metzler, Genita, Milstein, Matthew I., Mooney, Mary M., Murray, Andrew P., Mano, Hiroyuki, Nadler, Lee M., Hirano, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257268/
https://www.ncbi.nlm.nih.gov/pubmed/22279573
http://dx.doi.org/10.1371/journal.pone.0030229

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