Parsimonious Higher-Order Hidden Markov Models for Improved Array-CGH Analysis with Applications to Arabidopsis thaliana

Array-based comparative genomic hybridization (Array-CGH) is an important technology in molecular biology for the detection of DNA copy number polymorphisms between closely related genomes. Hidden Markov Models (HMMs) are popular tools for the analysis of Array-CGH data, but current methods are only...

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Detalles Bibliográficos
Autores principales: Seifert, Michael, Gohr, André, Strickert, Marc, Grosse, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257270/
https://www.ncbi.nlm.nih.gov/pubmed/22253580
http://dx.doi.org/10.1371/journal.pcbi.1002286

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