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Cytoplasmic Polyadenylation Element Binding Protein Deficiency Stimulates PTEN and Stat3 mRNA Translation and Induces Hepatic Insulin Resistance

The cytoplasmic polyadenylation element binding protein CPEB1 (CPEB) regulates germ cell development, synaptic plasticity, and cellular senescence. A microarray analysis of mRNAs regulated by CPEB unexpectedly showed that several encoded proteins are involved in insulin signaling. An investigation o...

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Detalles Bibliográficos
Autores principales:	Alexandrov, Ilya M., Ivshina, Maria, Jung, Dae Young, Friedline, Randall, Ko, Hwi Jin, Xu, Mei, O'Sullivan-Murphy, Bryan, Bortell, Rita, Huang, Yen-Tsung, Urano, Fumihiko, Kim, Jason K., Richter, Joel D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257279/ https://www.ncbi.nlm.nih.gov/pubmed/22253608 http://dx.doi.org/10.1371/journal.pgen.1002457

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