Inhibition of β-catenin Signaling by Nongenomic Action of Orphan Nuclear Receptor Nur77

Dysregulation of β-catenin turnover due to mutations of its regulatory proteins including APC and p53 is implicated in the pathogenesis of cancer. Thus, intensive effort is being made to search for alternative approaches to reduce abnormally activated β-catenin in cancer cells. Nur77, an orphan memb...

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Detalles Bibliográficos
Autores principales: Sun, Zhe, Cao, Xihua, Jiang, Miao-Miao, Qiu, Yingkun, Zhou, Hu, Chen, Liqun, Qin, Bin, Wu, Hua, Jiang, Fuquan, Chen, Jiebo, Liu, Jie, Dai, Yi, Chen, Hai-Feng, Hu, Qiong-ying, Wu, Zhen, Zeng, Jin-zhang, Yao, Xin-Sheng, Zhang, Xiao-kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257393/
https://www.ncbi.nlm.nih.gov/pubmed/21986938
http://dx.doi.org/10.1038/onc.2011.448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257393/
https://www.ncbi.nlm.nih.gov/pubmed/21986938
http://dx.doi.org/10.1038/onc.2011.448

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