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An intramolecular salt bridge drives the soluble domain of GTP-bound atlastin into the postfusion conformation

Endoplasmic reticulum (ER) network branching requires homotypic tethering and fusion of tubules mediated by the atlastin (ATL) guanosine triphosphatase (GTPase). Recent structural studies on the ATL soluble domain reveal two dimeric conformers proposed to correspond to a tethered prefusion state and...

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Detalles Bibliográficos
Autores principales:	Morin-Leisk, Jeanne, Saini, Simran G., Meng, Xin, Makhov, Alexander M., Zhang, Peijun, Lee, Tina H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257528/ https://www.ncbi.nlm.nih.gov/pubmed/22065636 http://dx.doi.org/10.1083/jcb.201105006

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