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Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye
Successful transition from embryonic to adult circulation is critical for survival of mammalian organisms. This shift occurs in the central cardiovascular circulation and in the eye as oxygen tension increases. However, its regulation is not well understood. We have used combinatorial gene deletion...
Autores principales: | Kurihara, Toshihide, Westenskow, Peter D., Krohne, Tim U., Aguilar, Edith, Johnson, Randall S., Friedlander, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257537/ https://www.ncbi.nlm.nih.gov/pubmed/22084310 http://dx.doi.org/10.1083/jcb.201107029 |
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