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Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye

Successful transition from embryonic to adult circulation is critical for survival of mammalian organisms. This shift occurs in the central cardiovascular circulation and in the eye as oxygen tension increases. However, its regulation is not well understood. We have used combinatorial gene deletion...

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Detalles Bibliográficos
Autores principales: Kurihara, Toshihide, Westenskow, Peter D., Krohne, Tim U., Aguilar, Edith, Johnson, Randall S., Friedlander, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257537/
https://www.ncbi.nlm.nih.gov/pubmed/22084310
http://dx.doi.org/10.1083/jcb.201107029

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