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Tim50’s presequence receptor domain is essential for signal driven transport across the TIM23 complex
N-terminal targeting signals (presequences) direct proteins across the TOM complex in the outer mitochondrial membrane and the TIM23 complex in the inner mitochondrial membrane. Presequences provide directionality to the transport process and regulate the transport machineries during translocation....
Autores principales: | Schulz, Christian, Lytovchenko, Oleksandr, Melin, Jonathan, Chacinska, Agnieszka, Guiard, Bernard, Neumann, Piotr, Ficner, Ralf, Jahn, Olaf, Schmidt, Bernhard, Rehling, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257539/ https://www.ncbi.nlm.nih.gov/pubmed/22065641 http://dx.doi.org/10.1083/jcb.201105098 |
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