Cargando…
Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells
Sulforaphane (SFN), an isothiocyanate derived from cruciferous vegetables, induces potent anti-proliferative effects in prostate cancer cells. One mechanism that may contribute to the anti-proliferative effects of SFN is the modulation of epigenetic marks, such as inhibition of histone deacetylase (...
Autores principales: | Hsu, Anna, Wong, Carmen P, Yu, Zhen, Williams, David E, Dashwood, Roderick H, Ho, Emily |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257546/ https://www.ncbi.nlm.nih.gov/pubmed/22303414 http://dx.doi.org/10.1186/1868-7083-3-3 |
Ejemplares similares
-
Effects of Sulforaphane and 3,3′-Diindolylmethane on Genome-Wide Promoter Methylation in Normal Prostate Epithelial Cells and Prostate Cancer Cells
por: Wong, Carmen P., et al.
Publicado: (2014) -
Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon
por: Rajendran, Praveen, et al.
Publicado: (2015) -
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates
por: Rajendran, Praveen, et al.
Publicado: (2013) -
Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly
por: Rajendran, Praveen, et al.
Publicado: (2011) -
SUV39H1/H3K9me3 attenuates sulforaphane-induced apoptotic signaling in PC3 prostate cancer cells
por: Watson, G W, et al.
Publicado: (2014)