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E–N-cadherin heterodimers define novel adherens junctions connecting endoderm-derived cells
Intercellular junctions play a pivotal role in tissue development and function and also in tumorigenesis. In epithelial cells, decrease or loss of E-cadherin, the hallmark molecule of adherens junctions (AJs), and increase of N-cadherin are widely thought to promote carcinoma progression and metasta...
Autores principales: | Straub, Beate K., Rickelt, Steffen, Zimbelmann, Ralf, Grund, Christine, Kuhn, Caecilia, Iken, Marcus, Ott, Michael, Schirmacher, Peter, Franke, Werner W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257573/ https://www.ncbi.nlm.nih.gov/pubmed/22105347 http://dx.doi.org/10.1083/jcb.201106023 |
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