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Comparative Effects of R- and S-equol and Implication of Transactivation Functions (AF-1 and AF-2) in Estrogen Receptor-Induced Transcriptional Activity
Equol, one of the main metabolites of daidzein, is a chiral compound with pleiotropic effects on cellular signaling. This property may induce activation/inhibition of the estrogen receptors (ER) a or b, and therefore, explain the beneficial/deleterious effects of equol on estrogen-dependent diseases...
Autores principales: | Shinkaruk, Svitlana, Carreau, Charlotte, Flouriot, Gilles, Bennetau-Pelissero, Catherine, Potier, Mylène |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257646/ https://www.ncbi.nlm.nih.gov/pubmed/22254026 http://dx.doi.org/10.3390/nu2030340 |
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