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Macrophage Phenotype Modulation by CXCL4 in Atherosclerosis
During atherogenesis, blood monocytes transmigrate into the subendothelial space and differentiate toward macrophages and foam cells. The major driver of monocyte–macrophage differentiation is macrophage colony-stimulating factor (M-CSF). M-CSF-induced macrophages are important promoters of atheroge...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257836/ https://www.ncbi.nlm.nih.gov/pubmed/22275902 http://dx.doi.org/10.3389/fphys.2012.00001 |