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Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase β

The base excision DNA repair (BER) pathway known to occur in Caenorhabditis elegans has not been well characterized. Even less is known about the DNA polymerase (pol) requirement for the gap-filling step during BER. We now report on characterization of in vitro uracil-DNA initiated BER in C. elegans...

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Detalles Bibliográficos
Autores principales: Asagoshi, Kenjiro, Lehmann, Wade, Braithwaite, Elena K., Santana-Santos, Lucas, Prasad, Rajendra, Freedman, Jonathan H., Van Houten, Bennett, Wilson, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258131/
https://www.ncbi.nlm.nih.gov/pubmed/21917855
http://dx.doi.org/10.1093/nar/gkr727