Cargando…

Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase β

The base excision DNA repair (BER) pathway known to occur in Caenorhabditis elegans has not been well characterized. Even less is known about the DNA polymerase (pol) requirement for the gap-filling step during BER. We now report on characterization of in vitro uracil-DNA initiated BER in C. elegans...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asagoshi, Kenjiro, Lehmann, Wade, Braithwaite, Elena K., Santana-Santos, Lucas, Prasad, Rajendra, Freedman, Jonathan H., Van Houten, Bennett, Wilson, Samuel H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258131/ https://www.ncbi.nlm.nih.gov/pubmed/21917855 http://dx.doi.org/10.1093/nar/gkr727

Ejemplares similares

The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ
por: Hirota, Kouji, et al.
Publicado: (2015)

Switching between polymerase and exonuclease sites in DNA polymerase ε
por: Ganai, Rais A., et al.
Publicado: (2015)

DNA polymerase beta participates in DNA End-joining
por: Ray, Sreerupa, et al.
Publicado: (2018)

Nucleotide excision repair of abasic DNA lesions
por: Kitsera, Nataliya, et al.
Publicado: (2019)

Metal-induced DNA translocation leads to DNA polymerase conformational activation
por: Kirby, Thomas W., et al.
Publicado: (2012)

Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases
por: Riva, Valentina, et al.
Publicado: (2020)

Critical amino acids in human DNA polymerases η and κ involved in erroneous incorporation of oxidized nucleotides
por: Katafuchi, Atsushi, et al.
Publicado: (2010)

MutL binds to 3′ resected DNA ends and blocks DNA polymerase access
por: Borsellini, Alessandro, et al.
Publicado: (2022)

Polymerase manager protein UmuD directly regulates Escherichia coli DNA polymerase III α binding to ssDNA
por: Chaurasiya, Kathy R., et al.
Publicado: (2013)

UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity
por: Cipolla, Lina, et al.
Publicado: (2019)

Inhibition of translesion DNA polymerase by archaeal reverse gyrase
por: Valenti, Anna, et al.
Publicado: (2009)

Loop 1 modulates the fidelity of DNA polymerase λ
por: Bebenek, Katarzyna, et al.
Publicado: (2010)

Strand displacement synthesis by yeast DNA polymerase ε
por: Ganai, Rais A., et al.
Publicado: (2016)

A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase β
por: Pei, De-Sheng, et al.
Publicado: (2011)

The enterohemorrhagic Escherichia coli insertion sequence-excision enhancer protein is a DNA polymerase with microhomology-mediated end-joining activity
por: Calvo, Patricia A, et al.
Publicado: (2023)

DNA polymerase β uses its lyase domain in a processive search for DNA damage
por: Howard, Michael J., et al.
Publicado: (2017)

Saccharomyces cerevisiae DNA polymerase IV overcomes Rad51 inhibition of DNA polymerase δ in Rad52-mediated direct-repeat recombination
por: Cerqueira, Paula G, et al.
Publicado: (2023)

Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage
por: Sabouri, Nasim, et al.
Publicado: (2008)

Novel ribonucleotide discrimination in the RNA polymerase-like two-barrel catalytic core of Family D DNA polymerases
por: Zatopek, Kelly M, et al.
Publicado: (2020)

Translesion-synthesis DNA polymerases participate in replication of the telomeres in Streptomyces
por: Tsai, Hsiu-Hui, et al.
Publicado: (2012)

DNA polymerase zeta is required for proliferation of normal mammalian cells
por: Lange, Sabine S., et al.
Publicado: (2012)

In vivo evidence for translesion synthesis by the replicative DNA polymerase δ
por: Hirota, Kouji, et al.
Publicado: (2016)

A polar filter in DNA polymerases prevents ribonucleotide incorporation
por: Johnson, Mary K, et al.
Publicado: (2019)

Mutagenic mechanisms of cancer-associated DNA polymerase ϵ alleles
por: Herzog, Mareike, et al.
Publicado: (2021)

The structure and duplex context of DNA interstrand crosslinks affects the activity of DNA polymerase η
por: Roy, Upasana, et al.
Publicado: (2016)

Bypass of DNA interstrand crosslinks by a Rev1–DNA polymerase ζ complex
por: Bezalel-Buch, Rachel, et al.
Publicado: (2020)

Human DNA polymerase α has a strong mutagenic potential at the initial steps of DNA synthesis
por: Lisova, Alisa E, et al.
Publicado: (2022)

Functional interplay of DnaE polymerase, DnaG primase and DnaC helicase within a ternary complex, and primase to polymerase hand-off during lagging strand DNA replication in Bacillus subtilis
por: Rannou, Olivier, et al.
Publicado: (2013)

Mismatch repair and DNA polymerase δ proofreading prevent catastrophic accumulation of leading strand errors in cells expressing a cancer-associated DNA polymerase ϵ variant
por: Bulock, Chelsea R, et al.
Publicado: (2020)

Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase ϵ variants at low dNTP levels
por: Barbari, Stephanie R, et al.
Publicado: (2022)

Mechano-chemical kinetics of DNA replication: identification of the translocation step of a replicative DNA polymerase
por: Morin, José A., et al.
Publicado: (2015)

RNA-guided DNA base damage repair via DNA polymerase-mediated nick translation
por: Tsegay, Pawlos S, et al.
Publicado: (2022)

Mechanism of strand displacement DNA synthesis by the coordinated activities of human mitochondrial DNA polymerase and SSB
por: Plaza-G.A., Ismael, et al.
Publicado: (2023)

Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases
por: Ho, The Vinh, et al.
Publicado: (2011)

Polymerase η suppresses telomere defects induced by DNA damaging agents
por: Pope-Varsalona, Hannah, et al.
Publicado: (2014)

DNA polymerase η contributes to genome-wide lagging strand synthesis
por: Kreisel, Katrin, et al.
Publicado: (2019)

The accessory subunit of mitochondrial DNA polymerase γ determines the DNA content of mitochondrial nucleoids in human cultured cells
por: Di Re, M., et al.
Publicado: (2009)

Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing
por: He, Liu, et al.
Publicado: (2023)

DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures
por: Northam, Matthew R., et al.
Publicado: (2014)

Real-time single-molecule studies of the motions of DNA polymerase fingers illuminate DNA synthesis mechanisms
por: Evans, Geraint W., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_48cj203tmro18tsi42l1u8ndno