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MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis
MiR-145 can regulate cell apoptosis, proliferation, neural development and stem cell differentiation. Previous studies indicate that miR-145 is downregulated in human colon cancer cells. However, the molecular mechanisms of miR-145 used to regulate colon carcinogenesis and angiogenesis remain to be...
Autores principales: | Xu, Qing, Liu, Ling-Zhi, Qian, Xu, Chen, Qi, Jiang, Yue, Li, Dan, Lai, Lihui, Jiang, Bing-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258133/ https://www.ncbi.nlm.nih.gov/pubmed/21917858 http://dx.doi.org/10.1093/nar/gkr730 |
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