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The human translation initiation multi-factor complex promotes methionyl-tRNA(i) binding to the 40S ribosomal subunit
The delivery of Met-tRNA(i) to the 40S ribosomal subunit is thought to occur by way of a ternary complex (TC) comprising eIF2, GTP and Met-tRNA(i). We have generated from purified human proteins a stable multifactor complex (MFC) comprising eIF1, eIF2, eIF3 and eIF5, similar to the MFC reported in y...
Autores principales: | Sokabe, Masaaki, Fraser, Christopher S., Hershey, John W. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258154/ https://www.ncbi.nlm.nih.gov/pubmed/21940399 http://dx.doi.org/10.1093/nar/gkr772 |
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