RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage

RNA-binding protein HuR modulates the stability and translational efficiency of messenger RNAs (mRNAs) encoding essential components of the cellular proliferation, growth and survival pathways. Consistent with these functions, HuR levels are often elevated in cancer cells and reduced in senescent an...

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Detalles Bibliográficos
Autores principales: Dai, Weijun, Zhang, Gen, Makeyev, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258158/
https://www.ncbi.nlm.nih.gov/pubmed/21948791
http://dx.doi.org/10.1093/nar/gkr783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258158/
https://www.ncbi.nlm.nih.gov/pubmed/21948791
http://dx.doi.org/10.1093/nar/gkr783

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