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AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis

AMP-activated protein kinase (AMPK) is a key energy sensor that regulates metabolism to maintain cellular energy balance. AMPK activation has also been proposed to mimic benefits of caloric restriction and exercise. Therefore, identifying downstream AMPK targets could elucidate new mechanisms for ma...

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Detalles Bibliográficos
Autores principales: Onyenwoke, Rob U., Forsberg, Lawrence J., Liu, Lucy, Williams, Tyisha, Alzate, Oscar, Brenman, Jay E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258181/
https://www.ncbi.nlm.nih.gov/pubmed/22114351
http://dx.doi.org/10.1091/mbc.E11-08-0699