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AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis
AMP-activated protein kinase (AMPK) is a key energy sensor that regulates metabolism to maintain cellular energy balance. AMPK activation has also been proposed to mimic benefits of caloric restriction and exercise. Therefore, identifying downstream AMPK targets could elucidate new mechanisms for ma...
Autores principales: | Onyenwoke, Rob U., Forsberg, Lawrence J., Liu, Lucy, Williams, Tyisha, Alzate, Oscar, Brenman, Jay E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258181/ https://www.ncbi.nlm.nih.gov/pubmed/22114351 http://dx.doi.org/10.1091/mbc.E11-08-0699 |
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