Role of Bcl-3 in solid tumors

Bcl-3 is an established oncogene in hematologic malignancies, such as B-cell chronic lymphocytic leukemias. Nevertheless, recent research has shown that it also participates in progression of diverse solid tumors. The present review summarizes the current knowledge of Bcl3 role in solid tumors progr...

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Detalles Bibliográficos
Autores principales: Maldonado, Vilma, Melendez-Zajgla, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258214/
https://www.ncbi.nlm.nih.gov/pubmed/22195643
http://dx.doi.org/10.1186/1476-4598-10-152
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author Maldonado, Vilma
Melendez-Zajgla, Jorge
author_facet Maldonado, Vilma
Melendez-Zajgla, Jorge
author_sort Maldonado, Vilma
collection PubMed
description Bcl-3 is an established oncogene in hematologic malignancies, such as B-cell chronic lymphocytic leukemias. Nevertheless, recent research has shown that it also participates in progression of diverse solid tumors. The present review summarizes the current knowledge of Bcl3 role in solid tumors progression, including some new insights in its possible molecular mechanisms of action.
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spelling pubmed-32582142012-01-14 Role of Bcl-3 in solid tumors Maldonado, Vilma Melendez-Zajgla, Jorge Mol Cancer Review Bcl-3 is an established oncogene in hematologic malignancies, such as B-cell chronic lymphocytic leukemias. Nevertheless, recent research has shown that it also participates in progression of diverse solid tumors. The present review summarizes the current knowledge of Bcl3 role in solid tumors progression, including some new insights in its possible molecular mechanisms of action. BioMed Central 2011-12-23 /pmc/articles/PMC3258214/ /pubmed/22195643 http://dx.doi.org/10.1186/1476-4598-10-152 Text en Copyright ©2011 Maldonado and Melendez-Zajgla; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Maldonado, Vilma
Melendez-Zajgla, Jorge
Role of Bcl-3 in solid tumors
title Role of Bcl-3 in solid tumors
title_full Role of Bcl-3 in solid tumors
title_fullStr Role of Bcl-3 in solid tumors
title_full_unstemmed Role of Bcl-3 in solid tumors
title_short Role of Bcl-3 in solid tumors
title_sort role of bcl-3 in solid tumors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258214/
https://www.ncbi.nlm.nih.gov/pubmed/22195643
http://dx.doi.org/10.1186/1476-4598-10-152
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