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Expression of a Neuroendocrine Gene Signature in Gastric Tumor Cells from CEA 424-SV40 Large T Antigen-Transgenic Mice Depends on SV40 Large T Antigen

BACKGROUND: A large fraction of murine tumors induced by transgenic expression of SV40 large T antigen (SV40 TAg) exhibits a neuroendocrine phenotype. It is unclear whether SV40 TAg induces the neuroendocrine phenotype by preferential transformation of progenitor cells committed to the neuroendocrin...

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Detalles Bibliográficos
Autores principales: Ihler, Fritz, Vetter, Elena Viviana, Pan, Jie, Kammerer, Robert, Debey-Pascher, Svenja, Schultze, Joachim L., Zimmermann, Wolfgang, Enders, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258231/
https://www.ncbi.nlm.nih.gov/pubmed/22253802
http://dx.doi.org/10.1371/journal.pone.0029846

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