A Modified RMCE-Compatible Rosa26 Locus for the Expression of Transgenes from Exogenous Promoters

Generation of gain-of-function transgenic mice by targeting the Rosa26 locus has been established as an alternative to classical transgenic mice produced by pronuclear microinjection. However, targeting transgenes to the endogenous Rosa26 promoter results in moderate ubiquitous expression and is not...

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Detalles Bibliográficos
Autores principales: Tchorz, Jan S., Suply, Thomas, Ksiazek, Iwona, Giachino, Claudio, Cloëtta, Dimitri, Danzer, Claus-Peter, Doll, Thierry, Isken, Andrea, Lemaistre, Marianne, Taylor, Verdon, Bettler, Bernhard, Kinzel, Bernd, Mueller, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258265/
https://www.ncbi.nlm.nih.gov/pubmed/22253858
http://dx.doi.org/10.1371/journal.pone.0030011

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