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BioDMET: a physiologically based pharmacokinetic simulation tool for assessing proposed solutions to complex biological problems

We developed a detailed, whole-body physiologically based pharmacokinetic (PBPK) modeling tool for calculating the distribution of pharmaceutical agents in the various tissues and organs of a human or animal as a function of time. Ordinary differential equations (ODEs) represent the circulation of b...

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Detalles Bibliográficos
Autores principales:	Graf, John F., Scholz, Bernhard J., Zavodszky, Maria I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258408/ https://www.ncbi.nlm.nih.gov/pubmed/22161221 http://dx.doi.org/10.1007/s10928-011-9229-x

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