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Chronic CaMKII inhibition blunts the cardiac contractile response to exercise training
Activation of the multifunctional Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) plays a critical role modulating cardiac function in both health and disease. Here, we determined the effect of chronic CaMKII inhibition during an exercise training program in healthy mice. CaMKII was inhibited...
Autores principales: | Kaurstad, Guri, Alves, Marcia N., Kemi, Ole J., Rolim, Natale, Høydal, Morten A., Wisløff, Helene, Stølen, Tomas O., Wisløff, Ulrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258410/ https://www.ncbi.nlm.nih.gov/pubmed/21614506 http://dx.doi.org/10.1007/s00421-011-1994-0 |
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