Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192

Transforming growth factor (TGF)-β has been shown to play a central role in the development of tubulointerstitial fibrosis, which can be corrected via treatment with paclitaxel. The biology of microRNA (miR) can be modulated by paclitaxel. We hypothesized that paclitaxel may attenuate renal fibrosis...

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Detalles Bibliográficos
Autores principales: Sun, Lin, Zhang, Dongshan, Liu, Fuyou, Xiang, Xudong, Ling, Guanghui, Xiao, Li, Liu, Yinghong, Zhu, Xuejing, Zhan, Ming, Yang, Yeyi, Kondeti, Vinay K, Kanwar, Yashpal S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258545/
https://www.ncbi.nlm.nih.gov/pubmed/21984124
http://dx.doi.org/10.1002/path.2961

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