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The Pro-inflammatory Role of TGFβ1: A Paradox?

TGFβ1 was initially identified as a potent chemotactic cytokine to initiate inflammation, but the autoimmune phenotype seen in TGFβ1 knockout mice reversed the dogma of TGFβ1 being a pro-inflammatory cytokine to predominantly an immune suppressor. The discovery of the role of TGFβ1 in Th17 cell acti...

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Detalles Bibliográficos
Autores principales:	Han, Gangwen, Li, Fulun, Singh, Tej Pratap, Wolf, Peter, Wang, Xiao-Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258562/ https://www.ncbi.nlm.nih.gov/pubmed/22253566

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