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Redo surgery risk in patients with cardiac prosthetic valve dysfunction

INTRODUCTION: The aim of the study was to analyse the risk factors of early and late mortality in patients undergoing the first reoperation for prosthetic valve dysfunction. MATERIAL AND METHODS: A retrospective observational study was performed in 194 consecutive patients (M = 75, F = 119; mean age...

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Autores principales: Maciejewski, Marek, Piestrzeniewicz, Katarzyna, Bielecka-Dąbrowa, Agata, Piechowiak, Monika, Jaszewski, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258715/
https://www.ncbi.nlm.nih.gov/pubmed/22291767
http://dx.doi.org/10.5114/aoms.2011.22078
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author Maciejewski, Marek
Piestrzeniewicz, Katarzyna
Bielecka-Dąbrowa, Agata
Piechowiak, Monika
Jaszewski, Ryszard
author_facet Maciejewski, Marek
Piestrzeniewicz, Katarzyna
Bielecka-Dąbrowa, Agata
Piechowiak, Monika
Jaszewski, Ryszard
author_sort Maciejewski, Marek
collection PubMed
description INTRODUCTION: The aim of the study was to analyse the risk factors of early and late mortality in patients undergoing the first reoperation for prosthetic valve dysfunction. MATERIAL AND METHODS: A retrospective observational study was performed in 194 consecutive patients (M = 75, F = 119; mean age 53.2 ±11 years) with a mechanical prosthetic valve (n = 103 cases; 53%) or bioprosthesis (91; 47%). Univariate and multivariate Cox statistical analysis was performed to determine risk factors of early and late mortality. RESULTS: The overall early mortality was 18.6%: 31.4% in patients with symptoms of NYHA functional class III-IV and 3.4% in pts in NYHA class I-II. Multivariate analysis identified symptoms of NYHA class III-IV and endocarditis as independent predictors of early mortality. The overall late mortality (> 30 days) was 8.2% (0.62% year/patient). Multivariate analysis identified age at the time of reoperation as a strong independent predictor of late mortality. CONCLUSIONS: Reoperation in patients with prosthetic valves, performed urgently, especially in patients with symptoms of NYHA class III-IV or in the case of endocarditis, bears a high mortality rate. Risk of planned reoperation, mostly in patients with symptoms of NYHA class I-II, does not differ from the risk of the first operation.
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spelling pubmed-32587152012-01-30 Redo surgery risk in patients with cardiac prosthetic valve dysfunction Maciejewski, Marek Piestrzeniewicz, Katarzyna Bielecka-Dąbrowa, Agata Piechowiak, Monika Jaszewski, Ryszard Arch Med Sci Clinical Research INTRODUCTION: The aim of the study was to analyse the risk factors of early and late mortality in patients undergoing the first reoperation for prosthetic valve dysfunction. MATERIAL AND METHODS: A retrospective observational study was performed in 194 consecutive patients (M = 75, F = 119; mean age 53.2 ±11 years) with a mechanical prosthetic valve (n = 103 cases; 53%) or bioprosthesis (91; 47%). Univariate and multivariate Cox statistical analysis was performed to determine risk factors of early and late mortality. RESULTS: The overall early mortality was 18.6%: 31.4% in patients with symptoms of NYHA functional class III-IV and 3.4% in pts in NYHA class I-II. Multivariate analysis identified symptoms of NYHA class III-IV and endocarditis as independent predictors of early mortality. The overall late mortality (> 30 days) was 8.2% (0.62% year/patient). Multivariate analysis identified age at the time of reoperation as a strong independent predictor of late mortality. CONCLUSIONS: Reoperation in patients with prosthetic valves, performed urgently, especially in patients with symptoms of NYHA class III-IV or in the case of endocarditis, bears a high mortality rate. Risk of planned reoperation, mostly in patients with symptoms of NYHA class I-II, does not differ from the risk of the first operation. Termedia Publishing House 2011-04 2011-05-17 /pmc/articles/PMC3258715/ /pubmed/22291767 http://dx.doi.org/10.5114/aoms.2011.22078 Text en Copyright © 2011 Termedia & Banach http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research
Maciejewski, Marek
Piestrzeniewicz, Katarzyna
Bielecka-Dąbrowa, Agata
Piechowiak, Monika
Jaszewski, Ryszard
Redo surgery risk in patients with cardiac prosthetic valve dysfunction
title Redo surgery risk in patients with cardiac prosthetic valve dysfunction
title_full Redo surgery risk in patients with cardiac prosthetic valve dysfunction
title_fullStr Redo surgery risk in patients with cardiac prosthetic valve dysfunction
title_full_unstemmed Redo surgery risk in patients with cardiac prosthetic valve dysfunction
title_short Redo surgery risk in patients with cardiac prosthetic valve dysfunction
title_sort redo surgery risk in patients with cardiac prosthetic valve dysfunction
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258715/
https://www.ncbi.nlm.nih.gov/pubmed/22291767
http://dx.doi.org/10.5114/aoms.2011.22078
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