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The effect of diabetic autonomic neuropathy on P-wave duration, dispersion and atrial fibrillation
INTRODUCTION: Atrial fibrillation (AF) is the most common sustained arrhythmia. Diabetic autonomic neuropathy (DAN) is a frequent complication of diabetes mellitus and has a negative impact on the cardiovascular system. There are no data about the occurrence of paroxysmal atrial fibrillation (PAF) i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258812/ https://www.ncbi.nlm.nih.gov/pubmed/22291825 http://dx.doi.org/10.5114/aoms.2011.25555 |
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author | Bissinger, Andrzej Grycewicz, Tomasz Grabowicz, Wlodzimierz Lubinski, Andrzej |
author_facet | Bissinger, Andrzej Grycewicz, Tomasz Grabowicz, Wlodzimierz Lubinski, Andrzej |
author_sort | Bissinger, Andrzej |
collection | PubMed |
description | INTRODUCTION: Atrial fibrillation (AF) is the most common sustained arrhythmia. Diabetic autonomic neuropathy (DAN) is a frequent complication of diabetes mellitus and has a negative impact on the cardiovascular system. There are no data about the occurrence of paroxysmal atrial fibrillation (PAF) in the population with DAN. MATERIAL AND METHODS: We analysed the data of 100 patients with PAF. The study population was divided into three groups: group I: 28 patients with diabetes mellitus (DM) and DAN, group II: 34 patients with DM without DAN, and group III: 38 patients without DM. P-wave duration (FPD) and dispersion (PWD) were measured during sinus rhythm and AF episodes were counted during 12 months of follow-up. RESULTS: Recurrence of PAF was higher in group I (47 episodes/year) compared to groups II and III (26 and 22 episodes/year) – p<0.01. The FPD was longer in group I (137.4 ±12.0 ms vs. 126 ±23.0 ms in II group and 129 ±18.3 ms in group III; p<0.001). The PWD was longer in patients with DAN (53 ±19 ms vs. 36 ±18 ms and 34 ± 20 ms, p<0.001). CONCLUSIONS: The results showed that the presence of DAN caused a significant increase in P-wave duration and dispersion, which might be responsible for the recurrence of AF. |
format | Online Article Text |
id | pubmed-3258812 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-32588122012-01-30 The effect of diabetic autonomic neuropathy on P-wave duration, dispersion and atrial fibrillation Bissinger, Andrzej Grycewicz, Tomasz Grabowicz, Wlodzimierz Lubinski, Andrzej Arch Med Sci Clinical Research INTRODUCTION: Atrial fibrillation (AF) is the most common sustained arrhythmia. Diabetic autonomic neuropathy (DAN) is a frequent complication of diabetes mellitus and has a negative impact on the cardiovascular system. There are no data about the occurrence of paroxysmal atrial fibrillation (PAF) in the population with DAN. MATERIAL AND METHODS: We analysed the data of 100 patients with PAF. The study population was divided into three groups: group I: 28 patients with diabetes mellitus (DM) and DAN, group II: 34 patients with DM without DAN, and group III: 38 patients without DM. P-wave duration (FPD) and dispersion (PWD) were measured during sinus rhythm and AF episodes were counted during 12 months of follow-up. RESULTS: Recurrence of PAF was higher in group I (47 episodes/year) compared to groups II and III (26 and 22 episodes/year) – p<0.01. The FPD was longer in group I (137.4 ±12.0 ms vs. 126 ±23.0 ms in II group and 129 ±18.3 ms in group III; p<0.001). The PWD was longer in patients with DAN (53 ±19 ms vs. 36 ±18 ms and 34 ± 20 ms, p<0.001). CONCLUSIONS: The results showed that the presence of DAN caused a significant increase in P-wave duration and dispersion, which might be responsible for the recurrence of AF. Termedia Publishing House 2011-11-08 2011-10 /pmc/articles/PMC3258812/ /pubmed/22291825 http://dx.doi.org/10.5114/aoms.2011.25555 Text en Copyright © 2011 Termedia & Banach http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Research Bissinger, Andrzej Grycewicz, Tomasz Grabowicz, Wlodzimierz Lubinski, Andrzej The effect of diabetic autonomic neuropathy on P-wave duration, dispersion and atrial fibrillation |
title | The effect of diabetic autonomic neuropathy on P-wave duration, dispersion and atrial fibrillation |
title_full | The effect of diabetic autonomic neuropathy on P-wave duration, dispersion and atrial fibrillation |
title_fullStr | The effect of diabetic autonomic neuropathy on P-wave duration, dispersion and atrial fibrillation |
title_full_unstemmed | The effect of diabetic autonomic neuropathy on P-wave duration, dispersion and atrial fibrillation |
title_short | The effect of diabetic autonomic neuropathy on P-wave duration, dispersion and atrial fibrillation |
title_sort | effect of diabetic autonomic neuropathy on p-wave duration, dispersion and atrial fibrillation |
topic | Clinical Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258812/ https://www.ncbi.nlm.nih.gov/pubmed/22291825 http://dx.doi.org/10.5114/aoms.2011.25555 |
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