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High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies from Drosophila S2 cells
Single-chain variable fragment (scFvs) antibodies are small polypeptides (∼26 kD) containing the heavy (V(H)) and light (V(L)) immunoglobulin domains of a parent antibody connected by a flexible linker. In addition to being frequently used in diagnostics and therapy for an increasing number of human...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258843/ https://www.ncbi.nlm.nih.gov/pubmed/22160929 http://dx.doi.org/10.1093/protein/gzr058 |