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Regulation of hTERT by BCR-ABL at multiple levels in K562 cells

BACKGROUND: The cytogenetic characteristic of Chronic Myeloid Leukemia (CML) is the formation of the Philadelphia chromosome gene product, BCR-ABL. Given that BCR-ABL is the specific target of Gleevec in CML treatment, we investigated the regulation of the catalytic component of telomerase, hTERT, b...

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Detalles Bibliográficos
Autores principales:	Chai, Juin Hsien, Zhang, Yong, Tan, Wei Han, Chng, Wee Joo, Li, Baojie, Wang, Xueying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259104/ https://www.ncbi.nlm.nih.gov/pubmed/22151181 http://dx.doi.org/10.1186/1471-2407-11-512

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