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Normalizing for individual cell population context in the analysis of high-content cellular screens

BACKGROUND: High-content, high-throughput RNA interference (RNAi) offers unprecedented possibilities to elucidate gene function and involvement in biological processes. Microscopy based screening allows phenotypic observations at the level of individual cells. It was recently shown that a cell'...

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Detalles Bibliográficos
Autores principales:	Knapp, Bettina, Rebhan, Ilka, Kumar, Anil, Matula, Petr, Kiani, Narsis A, Binder, Marco, Erfle, Holger, Rohr, Karl, Eils, Roland, Bartenschlager, Ralf, Kaderali, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259109/ https://www.ncbi.nlm.nih.gov/pubmed/22185194 http://dx.doi.org/10.1186/1471-2105-12-485

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