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TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling

BACKGROUND: TMPRSS2-ERG gene fusions occur in about 50% of all prostate cancer cases and represent promising markers for molecular subtyping. Although TMPRSS2-ERG fusion seems to be a critical event in prostate cancer, the precise functional role in cancer development and progression is still unclea...

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Detalles Bibliográficos
Autores principales:	Brase, Jan C, Johannes, Marc, Mannsperger, Heiko, Fälth, Maria, Metzger, Jennifer, Kacprzyk, Lukasz A, Andrasiuk, Tatjana, Gade, Stephan, Meister, Michael, Sirma, Hüseyin, Sauter, Guido, Simon, Ronald, Schlomm, Thorsten, Beißbarth, Tim, Korf, Ulrike, Kuner, Ruprecht, Sültmann, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259213/ https://www.ncbi.nlm.nih.gov/pubmed/22142399 http://dx.doi.org/10.1186/1471-2407-11-507

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