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Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination

Brain-derived neurotrophic factor (BDNF) is involved in neuronal and glial development and survival. While neurons and astrocytes are its main cellular source in the central nervous system (CNS), bioactive BDNF is also expressed in immune cells and in lesions of multiple sclerosis and its animal mod...

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Detalles Bibliográficos
Autores principales:	Lee, De-Hyung, Geyer, Eva, Flach, Anne-Christine, Jung, Klaus, Gold, Ralf, Flügel, Alexander, Linker, Ralf A., Lühder, Fred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259380/ https://www.ncbi.nlm.nih.gov/pubmed/22009304 http://dx.doi.org/10.1007/s00401-011-0890-3

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