Cerebrospinal Fluid BACE1 Activity and Brain Amyloid Load in Alzheimer's Disease

The secretase BACE1 is fundamentally involved in the development of cerebral amyloid pathology in Alzheimer's disease (AD). It has not been studied so far to what extent BACE1 activity in cerebrospinal fluid (CSF) mirrors in vivo amyloid load in AD. We explored associations between CSF BACE1 ac...

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Detalles Bibliográficos
Autores principales: Grimmer, Timo, Alexopoulos, Panagiotis, Tsolakidou, Amalia, Guo, Liang-Hao, Henriksen, Gjermund, Yousefi, Behrooz H., Förstl, Hans, Sorg, Christian, Kurz, Alexander, Drzezga, Alexander, Perneczky, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259508/
https://www.ncbi.nlm.nih.gov/pubmed/22272179
http://dx.doi.org/10.1100/2012/712048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259508/
https://www.ncbi.nlm.nih.gov/pubmed/22272179
http://dx.doi.org/10.1100/2012/712048

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