Process optimization for the preparation of oligomycin-loaded folate-conjugated chitosan nanoparticles as a tumor-targeted drug delivery system using a two-level factorial design method

Oligomycin-A (Oli-A), an anticancer drug, was loaded to the folate (FA)-conjugated chitosan as a tumor-targeted drug delivery system for the purpose of overcoming the nonspecific targeting characteristics and the hydrophobicity of the compound. The two-level factorial design (2-LFD) was applied to m...

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Detalles Bibliográficos
Autores principales: Zu, Yuangang, Zhao, Qi, Zhao, Xiuhua, Zu, Shuchong, Meng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260036/
https://www.ncbi.nlm.nih.gov/pubmed/22267927
http://dx.doi.org/10.2147/IJN.S27157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260036/
https://www.ncbi.nlm.nih.gov/pubmed/22267927
http://dx.doi.org/10.2147/IJN.S27157

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