Cigarette smoke increases TLR4 and TLR9 expression and induces cytokine production from CD8(+ )T cells in chronic obstructive pulmonary disease

BACKGROUND: Cigarette smoke is a major risk factor for chronic obstructive pulmonary disease (COPD), an inflammatory lung disorder. COPD is characterized by an increase in CD8(+ )T cells within the central and peripheral airways. We hypothesized that the CD8(+ )T cells in COPD patients have increase...

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Detalles Bibliográficos
Autores principales: Nadigel, Jessica, Préfontaine, David, Baglole, Carolyn J, Maltais, François, Bourbeau, Jean, Eidelman, David H, Hamid, Qutayba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260101/
https://www.ncbi.nlm.nih.gov/pubmed/22070100
http://dx.doi.org/10.1186/1465-9921-12-149

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