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Antibody degradation in tobacco plants: a predominantly apoplastic process
BACKGROUND: Interest in using plants for production of recombinant proteins such as monoclonal antibodies is growing, but proteolytic degradation, leading to a loss of functionality and complications in downstream purification, is still a serious problem. RESULTS: In this study, we investigated the...
Autores principales: | Hehle, Verena K, Paul, Matthew J, Drake, Pascal M, Ma, Julian KC, van Dolleweerd, Craig J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260137/ https://www.ncbi.nlm.nih.gov/pubmed/22208820 http://dx.doi.org/10.1186/1472-6750-11-128 |
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