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Phase I Evaluation of Intravenous Ascorbic Acid in Combination with Gemcitabine and Erlotinib in Patients with Metastatic Pancreatic Cancer
BACKGROUND: Preclinical data support further investigation of ascorbic acid in pancreatic cancer. There are currently insufficient safety data in human subjects, particularly when ascorbic acid is combined with chemotherapy. METHODS AND FINDINGS: 14 subjects with metastatic stage IV pancreatic cance...
Autores principales: | Monti, Daniel A., Mitchell, Edith, Bazzan, Anthony J., Littman, Susan, Zabrecky, George, Yeo, Charles J., Pillai, Madhaven V., Newberg, Andrew B., Deshmukh, Sandeep, Levine, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260161/ https://www.ncbi.nlm.nih.gov/pubmed/22272248 http://dx.doi.org/10.1371/journal.pone.0029794 |
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