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Manifold Learning for Human Population Structure Studies

The dimension of the population genetics data produced by next-generation sequencing platforms is extremely high. However, the “intrinsic dimensionality” of sequence data, which determines the structure of populations, is much lower. This motivates us to use locally linear embedding (LLE) which proj...

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Detalles Bibliográficos
Autores principales: Siu, Hoicheong, Jin, Li, Xiong, Momiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260176/
https://www.ncbi.nlm.nih.gov/pubmed/22272259
http://dx.doi.org/10.1371/journal.pone.0029901