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Efflux Protein Expression in Human Stem Cell-Derived Retinal Pigment Epithelial Cells
Retinal pigment epithelial (RPE) cells in the back of the eye nourish photoreceptor cells and form a selective barrier that influences drug transport from the blood to the photoreceptor cells. At the molecular level, ATP-dependent efflux transporters have a major role in drug delivery in human RPE....
Autores principales: | Juuti-Uusitalo, Kati, Vaajasaari, Hanna, Ryhänen, Tuomas, Narkilahti, Susanna, Suuronen, Riitta, Mannermaa, Eliisa, Kaarniranta, Kai, Skottman, Heli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260202/ https://www.ncbi.nlm.nih.gov/pubmed/22272278 http://dx.doi.org/10.1371/journal.pone.0030089 |
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