The Werner Syndrome Protein Is Distinguished from the Bloom Syndrome Protein by Its Capacity to Tightly Bind Diverse DNA Structures

Loss of Werner syndrome helicase-exonuclease (WRN) or of its homolog Bloom syndrome helicase (BLM) results in different inherited disorders. Whereas Werner syndrome is characterized by premature onset of aging and age-associated diseases, Bloom syndrome involves developmental abnormalities and incre...

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Detalles Bibliográficos
Autores principales: Kamath-Loeb, Ashwini, Loeb, Lawrence A., Fry, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260238/
https://www.ncbi.nlm.nih.gov/pubmed/22272300
http://dx.doi.org/10.1371/journal.pone.0030189

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