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Diversity of Plasmodium falciparum Chloroquine Resistance Transporter (pfcrt) Exon 2 Haplotypes in the Pacific from 1959 to 1979

Nearly one million deaths are attributed to malaria every year. Recent reports of multi-drug treatment failure of falciparum malaria underscore the need to understand the molecular basis of drug resistance. Multiple mutations in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) ar...

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Detalles Bibliográficos
Autores principales: Chan, Chim W., Spathis, Rita, Reiff, Dana M., McGrath, Stacy E., Garruto, Ralph M., Lum, J. Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260253/
https://www.ncbi.nlm.nih.gov/pubmed/22272308
http://dx.doi.org/10.1371/journal.pone.0030213