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Two PI 3-Kinases and One PI 3-Phosphatase Together Establish the Cyclic Waves of Phagosomal PtdIns(3)P Critical for the Degradation of Apoptotic Cells

Phosphatidylinositol 3-phosphate (PtdIns(3)P) is a signaling molecule important for many membrane trafficking events, including phagosome maturation. The level of PtdIns(3)P on phagosomes oscillates in two waves during phagosome maturation. However, the physiological significance of such oscillation...

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Detalles Bibliográficos
Autores principales: Lu, Nan, Shen, Qian, Mahoney, Timothy R., Neukomm, Lukas J., Wang, Ying, Zhou, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260314/
https://www.ncbi.nlm.nih.gov/pubmed/22272187
http://dx.doi.org/10.1371/journal.pbio.1001245

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