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Review of the literature and suggestions for the design of rodent survival studies for the identification of compounds that increase health and life span
Much of the literature describing the search for agents that increase the life span of rodents was found to suffer from confounds. One-hundred-six studies, absent 20 contradictory melatonin studies, of compounds or combinations of compounds were reviewed. Only six studies reported both life span ext...
Autor principal: | Spindler, Stephen Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260350/ https://www.ncbi.nlm.nih.gov/pubmed/21424790 http://dx.doi.org/10.1007/s11357-011-9224-6 |
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