Sensory neurons derived from diabetic rats have diminished internal Ca(2+) stores linked to impaired re-uptake by the endoplasmic reticulum

Distal symmetrical sensory neuropathy in diabetes involves the dying back of axons, and the pathology equates with axonal dystrophy generated under conditions of aberrant Ca(2+) signalling. Previous work has described abnormalities in Ca(2+) homoeostasis in sensory and dorsal horn neurons acutely is...

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Detalles Bibliográficos
Autores principales: Zherebitskaya, Elena, Schapansky, Jason, Akude, Eli, Smith, Darrell R, Van der Ploeg, Randy, Solovyova, Natasha, Verkhratsky, Alexei, Fernyhough, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260471/
https://www.ncbi.nlm.nih.gov/pubmed/22168362
http://dx.doi.org/10.1042/AN20110038

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