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Knowledge-Based, Central Nervous System (CNS) Lead Selection and Lead Optimization for CNS Drug Discovery

[Image: see text] The central nervous system (CNS) is the major area that is affected by aging. Alzheimer’s disease (AD), Parkinson’s disease (PD), brain cancer, and stroke are the CNS diseases that will cost trillions of dollars for their treatment. Achievement of appropriate blood–brain barrier (B...

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Detalles Bibliográficos
Autores principales:	Ghose, Arup K., Herbertz, Torsten, Hudkins, Robert L., Dorsey, Bruce D., Mallamo, John P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2011
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260741/ https://www.ncbi.nlm.nih.gov/pubmed/22267984 http://dx.doi.org/10.1021/cn200100h

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