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Monomeric α-Synuclein Binds Congo Red Micelles in a Disordered Manner

[Image: see text] The histological dye Congo Red (CR) previously has been shown to inhibit α-synuclein (aS) fibrillation, but the mode of this inhibition remained unclear. Because of favorable exchange kinetics, interaction between CR and aS lends itself to a detailed nuclear magnetic resonance stud...

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Detalles Bibliográficos
Autores principales: Maltsev, Alexander S., Grishaev, Alexander, Bax, Ad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260784/
https://www.ncbi.nlm.nih.gov/pubmed/22242826
http://dx.doi.org/10.1021/bi201435d