Inhibition of SREBP1 sensitizes cells to death ligands

Evasion of death receptor ligand-induced apoptosis contributs to cancer development and progression. To better understand mechanisms conferring resistance to death ligands, we screened an siRNA library to identify sequences that sensitize resistant cells to fas activating antibody (CH-11). From this...

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Detalles Bibliográficos
Autores principales: Eberhard, Yanina, Gronda, Marcela, Hurren, Rose, Datti, Alessandro, MacLean, Neil, Ketela, Troy, Moffat, Jason, Wrana, Jeffrey L., Schimmer, Aaron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260812/
https://www.ncbi.nlm.nih.gov/pubmed/21406729

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