Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo

Adherence of parasite-infected red blood cells (irbc) to the vascular endothelium of organs plays a key role in the pathogenesis of Plasmodium falciparum malaria. The prevailing hypothesis of why irbc adhere and sequester in tissues is that this acts as a mechanism of avoiding spleen-mediated cleara...

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Detalles Bibliográficos
Autores principales: Fonager, Jannik, Pasini, Erica M., Braks, Joanna A.M., Klop, Onny, Ramesar, Jai, Remarque, Edmond J., Vroegrijk, Irene O.C.M., van Duinen, Sjoerd G., Thomas, Alan W., Khan, Shahid M., Mann, Matthias, Kocken, Clemens H.M., Janse, Chris J., Franke-Fayard, Blandine M.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260870/
https://www.ncbi.nlm.nih.gov/pubmed/22184632
http://dx.doi.org/10.1084/jem.20110762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260870/
https://www.ncbi.nlm.nih.gov/pubmed/22184632
http://dx.doi.org/10.1084/jem.20110762

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