A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2

The molecular pathophysiology of myeloproliferative neoplasms (MPNs) remains poorly understood. Based on the observation that the transcription factor NF-E2 is often overexpressed in MPN patients, independent of the presence of other molecular aberrations, we generated mice expressing an NF-E2 trans...

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Detalles Bibliográficos
Autores principales: Kaufmann, Kai B., Gründer, Albert, Hadlich, Tobias, Wehrle, Julius, Gothwal, Monika, Bogeska, Ruzhica, Seeger, Thalia S., Kayser, Sarah, Pham, Kien-Binh, Jutzi, Jonas S., Ganzenmüller, Lucas, Steinemann, Doris, Schlegelberger, Brigitte, Wagner, Julia M., Jung, Manfred, Will, Britta, Steidl, Ulrich, Aumann, Konrad, Werner, Martin, Günther, Thomas, Schüle, Roland, Rambaldi, Alessandro, Pahl, Heike L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260873/
https://www.ncbi.nlm.nih.gov/pubmed/22231305
http://dx.doi.org/10.1084/jem.20110540

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