Gfi1b negatively regulates Rag expression directly and via the repression of FoxO1

Precise regulation of Rag (recombination-activating gene) expression is crucial to prevent genomic instability caused by the generation of Rag-mediated DNA breaks. Although mechanisms of Rag activation have been well characterized, the mechanism by which Rag expression is down-regulated in early B c...

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Detalles Bibliográficos
Autores principales: Schulz, Danae, Vassen, Lothar, Chow, Kwan T., McWhirter, Sarah M., Amin, Rupesh H., Möröy, Tarik, Schlissel, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260878/
https://www.ncbi.nlm.nih.gov/pubmed/22201127
http://dx.doi.org/10.1084/jem.20110645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260878/
https://www.ncbi.nlm.nih.gov/pubmed/22201127
http://dx.doi.org/10.1084/jem.20110645

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